{"id":6063,"date":"2023-10-10T11:09:29","date_gmt":"2023-10-10T11:09:29","guid":{"rendered":"https:\/\/www.ginefiv.com\/treatment\/fish-espermatozoides\/"},"modified":"2024-09-16T05:45:23","modified_gmt":"2024-09-16T05:45:23","slug":"fish-espermatozoides","status":"publish","type":"treatment","link":"https:\/\/www.ginefiv.com\/ca\/reproduccio-assistida\/fish-espermatozoides\/","title":{"rendered":"FISH en espermatozoides"},"content":{"rendered":"<section class=\"page-cover treatment-section has-thumbnail dark-theme\">     <div class=\"page-cover__container container treatment-page\">         <div class=\"row\">             <div class=\"col-12 col-lg-6 pt-4 pt-lg-0\">                 <div class=\"page-cover__heading\">                     <div class=\"page-cover__heading-wrapper treatment-heading\">                                                   <div class=\"page-cover__heading-subtitle heading-subtitle text-xxl\">                             <p>Reproducci\u00f3 assistida<\/p>                         <\/div>                          <div class=\"page-cover__heading-title heading-title title-display\">                             <h1 class=\"title-display\">FISH en espermatozoides<\/h1>                         <\/div>                                                      <div class=\"page-cover__heading-content text-lg\">                                 <p>La Hibridaci\u00f3 In Situ Fluorescent (FISH) \u00e9s una t\u00e8cnica que va revolucionar la citogen\u00e8tica cl\u00e0ssica en aplicar-hi coneixements de biologia molecular.<\/p>                             <\/div>                                                                      <\/div>                 <\/div>             <\/div>              <div class=\"col-12 col-lg-6 pt-5 pt-lg-0 pl-lg-5\">                 <div class=\"treatment-links-container\">                                     <\/div>             <\/div>         <\/div>     <\/div>               <div class=\"parallax-trigger fullsize page-cover-thumbnail treatment-thumbnail\" data-magic=\"parallax\">             <picture class=\"page-cover__picture parallax-trigger__item\" data-item=\"parallax-item\">                 <img decoding=\"async\" src=\"https:\/\/www.ginefiv.com\/wp-content\/uploads\/2023\/10\/fish-espermatozoides-header.jpg\" alt=\"FISH en espermatozoides\">             <\/picture>         <\/div>       <\/section>   <section class=\"wp-block-breadcrumbs\">   <div class=\"content-wrapper\">     <ul>                   <li>               <a href=\"https:\/\/www.ginefiv.com\/ca\/\" title=\"Ginefiv Espa\u00f1a\">                 Ginefiv              <\/a>             <\/li>                         <li>               <span class=\"current\" title=\"FISH en espermatozoides\">                 FISH en espermatozoides              <\/span>             <\/li>                 <\/ul>   <\/div> <\/section>    <div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\"> <div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\"> <p>Gr\u00e0cies a aquesta t\u00e8cnica podem estudiar el material gen\u00e8tic dels g\u00e0metes masculins fent servir unes sondes fluorescents que s\u2019uneixen espec\u00edficament a un determinat cromosoma i mitjan\u00e7ant les quals visualitzem quina quantitat n\u2019hi ha en cadascun dels espermatozoides del semen ejaculat.<\/p>    <p>L\u2019an\u00e0lisis de l\u2019ejaculat mitjan\u00e7ant FISH ens permetr\u00e0 determinar els nivells d\u2019espermatozoides amb dotaci\u00f3 cromos\u00f2mica an\u00f2mala i valorar si superen o no els l\u00edmits de normalitat.<\/p> <\/div> <\/div>   <section  class=\"image-text-block custom-block-spacing align-left\" data-magic=\"float-zigzag\">   <div class=\"container\">         <div class=\"row\">       <div class=\"img-col col-12 col-md-6\">                   <picture class=\"image-text-block__img-wrapper image-wrapper zigzag-element\">                         <img data-src=\"https:\/\/www.ginefiv.com\/wp-content\/uploads\/2023\/10\/cromosomas-1-540x380.jpg\" alt=\"\">           <\/picture>               <\/div>       <div class=\"text-col col-12 col-md-6\">         <div class=\"image-text-block__text-wrapper text-heading-block zigzag-element\">           <div class=\"image-text-block__text-wrapper__content\">             <div class=\"text-block-wrapper\">                             <h3 class=\"title-display\">El estudio de los cromosomas<\/h3>               <p>Qualsevol c\u00e8l\u00b7lula som\u00e0tica del cos hum\u00e0 t\u00e9 23 parells de cromosomes, \u00e9s a dir, 2 c\u00f2pies de cada cromosoma. En canvi, els g\u00e0metes humans (espermatozoides i o\u00f2cits), per ser cromos\u00f2micament normals, han de tenir 23 cromosomes, \u00e9s a dir, una \u00fanica c\u00f2pia de cada cromosoma. Per poder reduir-ne la dotaci\u00f3 cromos\u00f2mica a la meitat, es requereix un complex proc\u00e9s de divisi\u00f3 cel\u00b7lular anomenat meiosi. Si aquest proc\u00e9s no es porta a terme correctament, els cromosomes no es repartiran d\u2019una manera equivalent i es formaran g\u00e0metes amb anomalies cromos\u00f2miques.<\/p> <p>En el FISH d\u2019espermatozoides s\u2019analitzen habitualment 5 cromosomes: els cromosomes sexuals (X i Y) i els cromosomes 13, 18 i 21. Aquest estudi es pot ampliar a altres cromosomes si la hist\u00f2ria cl\u00ednica ho fa recomanable. El n\u00famero d\u2019espermatozoides analitzats sol ser de 2.000.<\/p>             <\/div>                       <\/div>         <\/div>       <\/div>     <\/div>   <\/div>  <\/section>  <section  class=\"text-block background-light custom-block-spacing\">   <div class=\"container\">     <div class=\"row\">       <div class=\"col-12\">         <div class=\"text-block__text-wrapper text-heading-block alignment-left\" data-magic=\"appear-in\">                     <h3 class=\"title-display\">Quan est\u00e0 indicat?<\/h3> <p>Diversos estudis han relacionat els casos de baixa qualitat seminal amb un percentatge elevat d\u2019anomalies cromos\u00f2miques en els espermatozoides. Per aquesta ra\u00f3 \u00e9s recomanable realitzar un FISH en els pacients amb un n\u00famero baix d\u2019espermatozoides: oligo o teratozoosp\u00e8rmia severa. Al mateix temps, per\u00f2, el principal inconvenient en aquests casos \u00e9s que la baixa concentraci\u00f3 esperm\u00e0tica dificulta la realitzaci\u00f3 de la prova.<\/p> <p>El FISH est\u00e0 indicat tamb\u00e9 en els seg\u00fcents casos:<\/p> <ul> <li>Falles d\u2019implantaci\u00f3<\/li> <li>Avortaments de repetici\u00f3<\/li> <li>Embar\u00e0s previ amb una cromosomopatia<\/li> <li>Pacients sotmesos a quimioter\u00e0pia o radioter\u00e0pia<\/li> <\/ul> <p>El resultat obtingut ajudar\u00e0 els professionals a escollir la\u00a0<strong><a href=\"https:\/\/www.ginefiv.com\/ca\/reproduccio-assistida\/\">t\u00e8cnica i el tractament de reproducci\u00f3 assistida<\/a><\/strong>\u00a0m\u00e9s adients en cada cas.<\/p>                   <\/div>       <\/div>     <\/div>   <\/div>  <\/section>   <div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\"> <div class=\"wp-block-column wp-column-is-centred is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:610px\"> <h2 class=\"wp-block-heading has-text-align-center\">Demana cita o consulta amb un especialista<\/h2>    <p class=\"has-text-align-center\">Tens l&#8217;opci\u00f3 de fer la teva primera consulta in situ a la cl\u00ednica o per videoconfer\u00e8ncia. 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