{"id":7982,"date":"2023-10-10T11:09:29","date_gmt":"2023-10-10T11:09:29","guid":{"rendered":"https:\/\/www.ginefiv.com\/treatment\/fish-espermatozoides\/"},"modified":"2024-09-16T05:46:06","modified_gmt":"2024-09-16T05:46:06","slug":"fish-test","status":"publish","type":"treatment","link":"https:\/\/www.ginefiv.com\/de\/assistierte-reproduktion\/fish-test\/","title":{"rendered":"Fluoreszenz-in-situ-Hybridisierung (FISH-Test)"},"content":{"rendered":"<section class=\"page-cover treatment-section has-thumbnail dark-theme\">     <div class=\"page-cover__container container treatment-page\">         <div class=\"row\">             <div class=\"col-12 col-lg-6 pt-4 pt-lg-0\">                 <div class=\"page-cover__heading\">                     <div class=\"page-cover__heading-wrapper treatment-heading\">                                                   <div class=\"page-cover__heading-subtitle heading-subtitle text-xxl\">                             <p>Assistierte Reproduktion<\/p>                         <\/div>                          <div class=\"page-cover__heading-title heading-title title-display\">                             <h1 class=\"title-display\">Fluoreszenz-in-situ-Hybridisierung (FISH-Test)<\/h1>                         <\/div>                                                      <div class=\"page-cover__heading-content text-lg\">                                 <p>Bei der Fluoreszenz-in-situ-Hybridisierung (FISH-Test) handelt es sich un eine Technik der Humangenetik die die klassischen zytogenetischen Methoden revoluzioniert hat, weil Sie Erkenntnisse der Molekularbiologie einbrigt.<\/p>                             <\/div>                                                                      <\/div>                 <\/div>             <\/div>              <div class=\"col-12 col-lg-6 pt-5 pt-lg-0 pl-lg-5\">                 <div class=\"treatment-links-container\">                                     <\/div>             <\/div>         <\/div>     <\/div>               <div class=\"parallax-trigger fullsize page-cover-thumbnail treatment-thumbnail\" data-magic=\"parallax\">             <picture class=\"page-cover__picture parallax-trigger__item\" data-item=\"parallax-item\">                 <img decoding=\"async\" src=\"https:\/\/www.ginefiv.com\/wp-content\/uploads\/2023\/10\/fish-espermatozoides-header.jpg\" alt=\"Fluoreszenz-in-situ-Hybridisierung (FISH-Test)\">             <\/picture>         <\/div>       <\/section>   <section class=\"wp-block-breadcrumbs\">   <div class=\"content-wrapper\">     <ul>                   <li>               <a href=\"https:\/\/www.ginefiv.com\/de\/\" title=\"Ginefiv Espa\u00f1a\">                 Ginefiv              <\/a>             <\/li>                         <li>               <span class=\"current\" title=\"Fluoreszenz-in-situ-Hybridisierung (FISH-Test)\">                 Fluoreszenz-in-situ-Hybridisierung (FISH-Test)              <\/span>             <\/li>                 <\/ul>   <\/div> <\/section>    <div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\"> <div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\"> <p>Dank dieser Technik k\u00f6nnen wir das genetische Material der m\u00e4nnlichen Gameten studieren; Hierbei werden mehrere fluoreszierende Gensonden verwendet, die sich an einem bestimmten Chromosom zusammenfinden, dank diesem Fluoreszenzfarbstoff an einen bestimmten Chromosomenabschnitt kann die Zahl jener Chromosomen jedes einzelnen Spermatozoos im Ejakulat sichtbar werden.<\/p>    <p>Die FISH-Analyse erlaubt uns das Ausmass der anormalen Chromosomen in den Spermatozoen festzustellen und zu sehen ob es das normale Limit \u00fcbersteigt oder nicht.<\/p> <\/div> <\/div>   <section  class=\"image-text-block custom-block-spacing align-left\" data-magic=\"float-zigzag\">   <div class=\"container\">         <div class=\"row\">       <div class=\"img-col col-12 col-md-6\">                   <picture class=\"image-text-block__img-wrapper image-wrapper zigzag-element\">                         <img data-src=\"https:\/\/www.ginefiv.com\/wp-content\/uploads\/2023\/10\/cromosomas-1-540x380.jpg\" alt=\"\">           <\/picture>               <\/div>       <div class=\"text-col col-12 col-md-6\">         <div class=\"image-text-block__text-wrapper text-heading-block zigzag-element\">           <div class=\"image-text-block__text-wrapper__content\">             <div class=\"text-block-wrapper\">                             <h3 class=\"title-display\">Chromosomenstudien<\/h3>               <p>Jede somatische Zelle des menschlichen K\u00f6rpers hat 23 Chromosomenpaare, d.h 2 Kopien von jedem Chromosom. Im Gegensatz hierzu, m\u00fcssen die Humangameten (Spermatozoen und Eizellen) um chromosomisch als normal zu gelten 23 Chromosome haben. D.h eine einzige Kopie von jedem Chromosom. Um ihre Chromosomenausstattung zur H\u00e4lfte zu reduzieren ist ein komplexer Prozess der Zellteilung, auch Meiose genannt, notwendig. Wenn dieser Prozess nicht korrekt zu Ende gef\u00fchrt wird, verteilen sich die Chromosomen nicht gleichm\u00e4ssig und es entstehen Gameten mit chromosomischen Abnormalit\u00e4ten.<\/p> <p>Beim FISH-Test der Spermatozoen werden f\u00fcr Gew\u00f6hnlich 5 Chromosomen analysiert. Die Sexualchromosome (X und Y) und die Chromosomen 13, 18 und 21. Diese Studie kann sich auf andere Chromosomen ausweiten wenn es sich laut PatientInnenakte empfiehlt. Die Anzahl der analysierten Spermatozoen ist normalerweise 2.000.<\/p>             <\/div>                       <\/div>         <\/div>       <\/div>     <\/div>   <\/div>  <\/section>  <section  class=\"text-block background-light custom-block-spacing\">   <div class=\"container\">     <div class=\"row\">       <div class=\"col-12\">         <div class=\"text-block__text-wrapper text-heading-block alignment-left\" data-magic=\"appear-in\">                     <h3 class=\"title-display\">Wann ist der Test empfehlenswert?<\/h3> <p>Mehrfachstudien haben ergeben, dass F\u00e4lle von niedriger Spermienqualit\u00e4t und hohen Chromosomalanomalien in direktem Zusammenhang stehen. Deshalb ist es ratsam, den FISH-Test f\u00fcr diejenigen Patienten durchzuf\u00fchren, die eine niedrige Spermatozoenanzahl haben: Oligo-teratozoospermie. Jedoch ist gleichzeitig die Schwierigkeit mit so wenig Spermienkonzentration \u00fcberhaupt diesen Test ausf\u00fchren zu k\u00f6nnen.<\/p> <p>FISH ist ebenso in folgenden F\u00e4llen empfohlen:<\/p> <ul> <li>Implantationsfehlschl\u00e4ge<\/li> <li>Mehrfachfehlgeburten<\/li> <li>Vorherige Schwangerschaft mit Chromosomsch\u00e4den<\/li> <li>Patienten mit Chemo -oder Raditherapie<\/li> <\/ul> <p>Das Ergebnis hilft dem spezialiserten Personal die bestm\u00f6gliche Technik und Reproduktionsbehandlung f\u00fcr Sie zu finden.<\/p>                   <\/div>       <\/div>     <\/div>   <\/div>  <\/section>   <div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\"> <div class=\"wp-block-column wp-column-is-centred is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:610px\"> <h3 class=\"wp-block-heading has-text-align-center\">Reservieren Sie ein Gespr\u00e4ch mit dem Spezialisten<\/h3>    <p class=\"has-text-align-center\">R\u00e4umen Sie Zweifel \u00fcber den FISH-Test aus und informieren Sie sich bei unseren Spezialisten \u00fcber Alternativen in Ihrem Fall.<\/p>    <div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-a89b3969 wp-block-buttons-is-layout-flex\"> <div class=\"wp-block-button\"><a class=\"wp-block-button__link has-orange-background-color has-background wp-element-button\" href=\"https:\/\/www.ginefiv.com\/de\/kontakt\/\" style=\"border-radius:5px\">Kontakt<\/a><\/div> <\/div> <\/div> <\/div>    <div class=\"wp-block-columns alignfull has-turquoise-teal-background-color has-background is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\"> <div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\"> <section class=\"grid-icons-block content-wrapper\">        <div class=\"grid-icon\">             <picture class=\"grid-icon__thumbnail\">         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