{"id":6722,"date":"2023-10-10T10:57:29","date_gmt":"2023-10-10T10:57:29","guid":{"rendered":"https:\/\/www.ginefiv.com\/treatment\/macs\/"},"modified":"2024-11-22T09:46:15","modified_gmt":"2024-11-22T09:46:15","slug":"macs","status":"publish","type":"treatment","link":"https:\/\/www.ginefiv.com\/fr\/pma\/macs\/","title":{"rendered":"MACS"},"content":{"rendered":"<section class=\"page-cover treatment-section has-thumbnail dark-theme\">     <div class=\"page-cover__container container treatment-page\">         <div class=\"row\">             <div class=\"col-12 col-lg-6 pt-4 pt-lg-0\">                 <div class=\"page-cover__heading\">                     <div class=\"page-cover__heading-wrapper treatment-heading\">                                                   <div class=\"page-cover__heading-subtitle heading-subtitle text-xxl\">                             <p>PMA<\/p>                         <\/div>                          <div class=\"page-cover__heading-title heading-title title-display\">                             <h1 class=\"title-display\">MACS (Magnetic Activated Cell Sorting)<\/h1>                         <\/div>                                                      <div class=\"page-cover__heading-content text-lg\">                                 <p>Comme nous l&rsquo;expliquons ci-apr\u00e8s, la technique MACS permet d&rsquo;optimiser la s\u00e9lection des spermatozo\u00efdes avant de les utiliser dans des proc\u00e9d\u00e9s de procr\u00e9ation m\u00e9dicalement assist\u00e9e.<\/p>                             <\/div>                                                                      <\/div>                 <\/div>             <\/div>              <div class=\"col-12 col-lg-6 pt-5 pt-lg-0 pl-lg-5\">                 <div class=\"treatment-links-container\">                                             <div class=\"treatment-links-container__links text-lg\">                             <ul> <li><a href=\"#quest\" rel=\"noopener\">Le MACS, qu&rsquo;est-ce que c&rsquo;est ?<\/a><\/li> <li><a href=\"#en-quoi\" rel=\"noopener\">En quoi consiste cette technique ?<\/a><\/li> <li><a href=\"#dans\" rel=\"noopener\">Dans quels cas cette technique est-elle pr\u00e9conis\u00e9e ?<\/a><\/li> <li><a href=\"#votre\" rel=\"noopener\">Votre premi\u00e8re visite<\/a><\/li> <\/ul>                         <\/div>                                     <\/div>             <\/div>         <\/div>     <\/div>               <div class=\"parallax-trigger fullsize page-cover-thumbnail treatment-thumbnail\" data-magic=\"parallax\">             <picture class=\"page-cover__picture parallax-trigger__item\" data-item=\"parallax-item\">                 <img decoding=\"async\" src=\"https:\/\/www.ginefiv.com\/wp-content\/uploads\/2023\/06\/inseminacion_hero.webp\" alt=\"MACS\">             <\/picture>         <\/div>       <\/section>   <section class=\"wp-block-breadcrumbs\">   <div class=\"content-wrapper\">     <ul>                   <li>               <a href=\"https:\/\/www.ginefiv.com\/fr\/\" title=\"Ginefiv Espa\u00f1a\">                 Ginefiv              <\/a>             <\/li>                         <li>               <span class=\"current\" title=\"MACS\">                 MACS              <\/span>             <\/li>                 <\/ul>   <\/div> <\/section>    <div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\"> <div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\"> <p>Le MACS est une technique de s\u00e9lection des spermatozo\u00efdes particuli\u00e8rement indiqu\u00e9e dans les cas d\u2019infertilit\u00e9 masculine associ\u00e9s \u00e0 un taux pathologique de fragmentation de l\u2019ADN spermatique, aussi bien dans les traitements \u00e0 base de f\u00e9condation in vitro que dans l\u2019ins\u00e9mination artificielle. Elle est susceptible d\u2019am\u00e9liorer le taux de f\u00e9condation de 13 %.<\/p> <\/div> <\/div>    <div class=\"wp-block-columns alignfull has-turquoise-teal-background-color has-background is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\"> <div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\"> <section class=\"grid-icons-block content-wrapper\">        <div class=\"grid-icon\">             <picture class=\"grid-icon__thumbnail\">         <img loading=\"lazy\" decoding=\"async\" width=\"700\" height=\"700\" src=\"https:\/\/www.ginefiv.com\/wp-content\/uploads\/2023\/10\/35anos.png\" class=\"attachment-large size-large\" alt=\"\" srcset=\"https:\/\/www.ginefiv.com\/wp-content\/uploads\/2023\/10\/35anos.png 700w, https:\/\/www.ginefiv.com\/wp-content\/uploads\/2023\/10\/35anos-300x300.png 300w, https:\/\/www.ginefiv.com\/wp-content\/uploads\/2023\/10\/35anos-150x150.png 150w, https:\/\/www.ginefiv.com\/wp-content\/uploads\/2023\/10\/35anos-420x420.png 420w\" sizes=\"auto, (max-width: 700px) 100vw, 700px\" \/>      <\/picture>             <div class=\"grid-icon__text\">         35 ans d&rsquo;exp\u00e9rience      <\/div>     <\/div>         <div class=\"grid-icon\">             <picture class=\"grid-icon__thumbnail\">         <img loading=\"lazy\" decoding=\"async\" width=\"700\" height=\"700\" src=\"https:\/\/www.ginefiv.com\/wp-content\/uploads\/2023\/10\/mano-cruz.png\" class=\"attachment-large size-large\" alt=\"\" srcset=\"https:\/\/www.ginefiv.com\/wp-content\/uploads\/2023\/10\/mano-cruz.png 700w, https:\/\/www.ginefiv.com\/wp-content\/uploads\/2023\/10\/mano-cruz-300x300.png 300w, https:\/\/www.ginefiv.com\/wp-content\/uploads\/2023\/10\/mano-cruz-150x150.png 150w, https:\/\/www.ginefiv.com\/wp-content\/uploads\/2023\/10\/mano-cruz-420x420.png 420w\" sizes=\"auto, (max-width: 700px) 100vw, 700px\" \/>      <\/picture>             <div class=\"grid-icon__text\">          S\u00e9curit\u00e9 garantie       <\/div>     <\/div>         <div class=\"grid-icon\">             <picture class=\"grid-icon__thumbnail\">         <img loading=\"lazy\" decoding=\"async\" width=\"700\" height=\"700\" src=\"https:\/\/www.ginefiv.com\/wp-content\/uploads\/2023\/10\/auriculares.png\" class=\"attachment-large size-large\" alt=\"\" srcset=\"https:\/\/www.ginefiv.com\/wp-content\/uploads\/2023\/10\/auriculares.png 700w, https:\/\/www.ginefiv.com\/wp-content\/uploads\/2023\/10\/auriculares-300x300.png 300w, https:\/\/www.ginefiv.com\/wp-content\/uploads\/2023\/10\/auriculares-150x150.png 150w, https:\/\/www.ginefiv.com\/wp-content\/uploads\/2023\/10\/auriculares-420x420.png 420w\" sizes=\"auto, (max-width: 700px) 100vw, 700px\" \/>      <\/picture>             <div class=\"grid-icon__text\">         Assistance personnalis\u00e9      <\/div>     <\/div>         <div class=\"grid-icon\">             <picture class=\"grid-icon__thumbnail\">         <img loading=\"lazy\" decoding=\"async\" width=\"700\" height=\"700\" src=\"https:\/\/www.ginefiv.com\/wp-content\/uploads\/2023\/10\/ovulo.png\" class=\"attachment-large size-large\" alt=\"\" srcset=\"https:\/\/www.ginefiv.com\/wp-content\/uploads\/2023\/10\/ovulo.png 700w, https:\/\/www.ginefiv.com\/wp-content\/uploads\/2023\/10\/ovulo-300x300.png 300w, https:\/\/www.ginefiv.com\/wp-content\/uploads\/2023\/10\/ovulo-150x150.png 150w, https:\/\/www.ginefiv.com\/wp-content\/uploads\/2023\/10\/ovulo-420x420.png 420w\" sizes=\"auto, (max-width: 700px) 100vw, 700px\" \/>      <\/picture>             <div class=\"grid-icon__text\">         A la pointe de la technologie      <\/div>     <\/div>         <div class=\"grid-icon\">             <picture class=\"grid-icon__thumbnail\">         <img loading=\"lazy\" decoding=\"async\" width=\"700\" height=\"700\" src=\"https:\/\/www.ginefiv.com\/wp-content\/uploads\/2023\/10\/medalla.png\" class=\"attachment-large size-large\" alt=\"\" srcset=\"https:\/\/www.ginefiv.com\/wp-content\/uploads\/2023\/10\/medalla.png 700w, https:\/\/www.ginefiv.com\/wp-content\/uploads\/2023\/10\/medalla-300x300.png 300w, https:\/\/www.ginefiv.com\/wp-content\/uploads\/2023\/10\/medalla-150x150.png 150w, https:\/\/www.ginefiv.com\/wp-content\/uploads\/2023\/10\/medalla-420x420.png 420w\" sizes=\"auto, (max-width: 700px) 100vw, 700px\" \/>      <\/picture>             <div class=\"grid-icon__text\">         Taux de r\u00e9ussite \u00e9lev\u00e9      <\/div>     <\/div>         <div class=\"grid-icon\">             <picture class=\"grid-icon__thumbnail\">         <img loading=\"lazy\" decoding=\"async\" width=\"700\" height=\"700\" src=\"https:\/\/www.ginefiv.com\/wp-content\/uploads\/2023\/10\/mano-ok.png\" class=\"attachment-large size-large\" alt=\"\" srcset=\"https:\/\/www.ginefiv.com\/wp-content\/uploads\/2023\/10\/mano-ok.png 700w, https:\/\/www.ginefiv.com\/wp-content\/uploads\/2023\/10\/mano-ok-300x300.png 300w, https:\/\/www.ginefiv.com\/wp-content\/uploads\/2023\/10\/mano-ok-150x150.png 150w, https:\/\/www.ginefiv.com\/wp-content\/uploads\/2023\/10\/mano-ok-420x420.png 420w\" sizes=\"auto, (max-width: 700px) 100vw, 700px\" \/>      <\/picture>             <div class=\"grid-icon__text\">         Tarifs \u00e9conomiques      <\/div>     <\/div>     <\/section><\/div> <\/div>   <section id=\"quest\" class=\"image-text-block custom-block-spacing align-left\" data-magic=\"float-zigzag\">   <div class=\"container\">           <div class=\"row\">         <div class=\"title-col col-12 col-md-6\"><h3 class=\"title-display\">Le MACS, qu&rsquo;est-ce que c&rsquo;est ?<\/h3> <\/div>       <\/div>         <div class=\"row\">       <div class=\"img-col col-12 col-md-6\">                   <picture class=\"image-text-block__img-wrapper image-wrapper zigzag-element\">                         <img data-src=\"https:\/\/www.ginefiv.com\/wp-content\/uploads\/2023\/08\/diagnostico-5-540x380.webp\" alt=\"\">           <\/picture>               <\/div>       <div class=\"text-col col-12 col-md-6\">         <div class=\"image-text-block__text-wrapper text-heading-block zigzag-element\">           <div class=\"image-text-block__text-wrapper__content\">             <div class=\"text-block-wrapper\">                                           <p>C\u2019est une technique qui permet une s\u00e9lection immuno-magn\u00e9tique des spermatozo\u00efdes les plus sains et les plus aptes \u00e0 f\u00e9conder l\u2019ovule, en les s\u00e9parant de ceux qui pr\u00e9sentent des marqueurs apoptotiques, appel\u00e9s \u00e0 dispara\u00eetre. Cette technique est con\u00e7ue pour \u00eatre utilis\u00e9e aussi bien dans le cadre d\u2019une ins\u00e9mination artificielle que pour les traitements de f\u00e9condation in vitro ou d\u2019<a href=\"https:\/\/www.ginefiv.com\/fr\/pma\/icsi\/\" style=\"font-weight: bold; text-decoration: underline;\">ICSI<\/a>.<\/p> <p>L\u2019apoptose (ou mort cellulaire programm\u00e9e) est un processus de contr\u00f4le du cycle cellulaire. Pendant la spermatog\u00e9n\u00e8se, elle se d\u00e9clenche par exemple lorsque des dommages cellulaires tels que la <a href=\"https:\/\/www.ginefiv.com\/fr\/pma\/test-fragmentation-adn-spermatique\/\" rel=\"noopener\" id=\"__hsNewLink\" style=\"font-weight: bold; text-decoration: underline;\">fragmentation de l\u2019ADN spermatique<\/a> sont d\u00e9tect\u00e9s.<\/p>             <\/div>                       <\/div>         <\/div>       <\/div>     <\/div>   <\/div>  <\/section>   <section  class=\"banner-testimonies-block-container\">     <div class=\"banner-testimonies-bg\" style=\"background-image:url(https:\/\/www.ginefiv.com\/wp-content\/themes\/wac-theme\/assets\/images\/bg-testimonial-logo.svg)\"><\/div>     <div class=\"banner-testimonies-block\">         <div class=\"banner-testimonies-block__content\">             <!--h3 class=\"testimonies-block__title heading-md\"-->                 R\u00eaves accomplis            <!--\/h3-->             <div class=\"testimonies-block__cards-container\" data-slider=\"testimony\">                                     <div class=\"testimony\">                         <img decoding=\"async\" class=\"testimony__decorator\" src=\"https:\/\/www.ginefiv.com\/wp-content\/themes\/wac-theme\/assets\/images\/icons\/testimony_decorator.png\" alt=\"Testimony decorator\">                         <div class=\"testimony__text\">                             <p>Une magnifique exp\u00e9rience \u00e0 la clinique de Barcelone, avec un suivi tr\u00e8s professionnel, une \u00e9quipe \u00e0 l&rsquo;\u00e9coute et disponible. Tout a pu \u00eatre commenc\u00e9 tr\u00e8s rapidement et nous avons eu notre fille apr\u00e8s la premi\u00e8re FIV. Un grand merci !<\/p>                         <\/div>                         <p class=\"testimony__author\">                             Sarah T                        <\/p>                     <\/div>                                     <div class=\"testimony\">                         <img decoding=\"async\" class=\"testimony__decorator\" src=\"https:\/\/www.ginefiv.com\/wp-content\/themes\/wac-theme\/assets\/images\/icons\/testimony_decorator.png\" alt=\"Testimony decorator\">                         <div class=\"testimony__text\">                             <p><span>\u201csi nous pouvions mettre plus d&rsquo;\u00e9toiles, on ne saurait mieux exprim\u00e9 nos remerciement \u00e0 Ginefiv, personnel accueillant , aimable et disponible! nous recommandons cette clinique volontiers Milles \u00e9toiles ne suffisent pas! merci GINEFIV\u201d<\/span><\/p>                         <\/div>                         <p class=\"testimony__author\">                             angel Lukusa                        <\/p>                     <\/div>                                     <div class=\"testimony\">                         <img decoding=\"async\" class=\"testimony__decorator\" src=\"https:\/\/www.ginefiv.com\/wp-content\/themes\/wac-theme\/assets\/images\/icons\/testimony_decorator.png\" alt=\"Testimony decorator\">                         <div class=\"testimony__text\">                             <p>Nous sommes les heureuses maman de deux enfants via fiv. Seul point \u00e0 am\u00e9liorer selon moi la transmission des ordonnances suite aux echographies<\/p>                         <\/div>                         <p class=\"testimony__author\">                             Lucie Raoul                        <\/p>                     <\/div>                                     <div class=\"testimony\">                         <img decoding=\"async\" class=\"testimony__decorator\" src=\"https:\/\/www.ginefiv.com\/wp-content\/themes\/wac-theme\/assets\/images\/icons\/testimony_decorator.png\" alt=\"Testimony decorator\">                         <div class=\"testimony__text\">                             <p>\u00ab\u00a0Une magnifique aventure rendue possible gr\u00e2ce \u00e0 l\u2019accompagnement personnalis\u00e9 et le professionnalisme de la clinique Ginefiv.\u201d<\/p>                         <\/div>                         <p class=\"testimony__author\">                             Hdkzb Vfjfjdk                        <\/p>                     <\/div>                                     <div class=\"testimony\">                         <img decoding=\"async\" class=\"testimony__decorator\" src=\"https:\/\/www.ginefiv.com\/wp-content\/themes\/wac-theme\/assets\/images\/icons\/testimony_decorator.png\" alt=\"Testimony decorator\">                         <div class=\"testimony__text\">                             <p>Merci Ginefiv! Gr\u00e2ce \u00e0 vous et \u00e0 mon gyn\u00e9co Dr Douard je suis maman d une petite depuis un an apr\u00e8s . Ne vous d\u00e9couragez pas et gardez espoir les filles tout est possible en gardant le moral et en restant positif .<\/p>                         <\/div>                         <p class=\"testimony__author\">                             papouha ferhat                        <\/p>                     <\/div>                                     <div class=\"testimony\">                         <img decoding=\"async\" class=\"testimony__decorator\" src=\"https:\/\/www.ginefiv.com\/wp-content\/themes\/wac-theme\/assets\/images\/icons\/testimony_decorator.png\" alt=\"Testimony decorator\">                         <div class=\"testimony__text\">                             <p>\u00ab\u00a0Personnel tr\u00e8s \u00e0 l&rsquo;\u00e9coute et attentif mon beaucoup soutenu jusqu&rsquo;au bout de mon parcours et maintenant j&rsquo;ai un beau petit gar\u00e7on alors je les remercie\u00a0\u00bb<\/p>                         <\/div>                         <p class=\"testimony__author\">                             Sherline Michel                        <\/p>                     <\/div>                             <\/div>         <\/div>     <\/div> <\/section>  <section  class=\"text-block background-light custom-block-spacing\">   <div class=\"container\">     <div class=\"row\">       <div class=\"col-12\">         <div class=\"text-block__text-wrapper text-heading-block alignment-left\" data-magic=\"appear-in\">                     <p>Plusieurs \u00e9tudes r\u00e9alis\u00e9es aupr\u00e8s de patients souffrant d\u2019infertilit\u00e9 ont montr\u00e9 qu\u2019il existe un nombre \u00e9lev\u00e9 de spermatozo\u00efdes dans leur \u00e9jaculat qui pr\u00e9sentent des marqueurs apoptiques, r\u00e9v\u00e9lant donc que le m\u00e9canisme de contr\u00f4le propre n\u2019a pas fonctionn\u00e9 correctement ou que la proportion de cellules endommag\u00e9es est tr\u00e8s \u00e9lev\u00e9e. Ceci peut \u00eatre d\u00fb aussi bien \u00e0 des facteurs intrins\u00e8ques qu\u2019\u00e0 des facteurs externes (tabagisme, stress, fi\u00e8vre, varicoc\u00e8le, etc.).<\/p> <p>C\u2019est l\u00e0 qu\u2019intervient la s\u00e9lection cellulaire immuno-magn\u00e9tique ou MACS. Ce proc\u00e9d\u00e9 consiste \u00e0 faire passer les spermatozo\u00efdes \u00e0 travers une colonne magn\u00e9tique, de sorte que ceux qui portent des marqueurs apoptotiques sur leur membrane sont retenus dans cette colonne de filtrage, tandis que les spermatozo\u00efdes sains et aptes \u00e0 f\u00e9conder l\u2019ovule sont laiss\u00e9s libres. Cette s\u00e9lection est susceptible d\u2019am\u00e9liorer le taux de f\u00e9condation de 13 %.<\/p>                   <\/div>       <\/div>     <\/div>   <\/div>  <\/section>  <section id=\"en-quoi\" class=\"image-text-block custom-block-spacing align-left\" data-magic=\"float-zigzag\">   <div class=\"container\">         <div class=\"row\">       <div class=\"img-col col-12 col-md-6\">                   <picture class=\"image-text-block__img-wrapper image-wrapper zigzag-element\">                         <img data-src=\"https:\/\/www.ginefiv.com\/wp-content\/uploads\/2023\/10\/tecnica-2-540x380.webp\" alt=\"\">           <\/picture>               <\/div>       <div class=\"text-col col-12 col-md-6\">         <div class=\"image-text-block__text-wrapper text-heading-block zigzag-element\">           <div class=\"image-text-block__text-wrapper__content\">             <div class=\"text-block-wrapper\">                             <h3 class=\"title-display\">En quoi consiste cette technique ?<\/h3>               <p>La technique repose sur l\u2019utilisation de microsph\u00e8res magn\u00e9tiques, dont les parois sont recouvertes de mol\u00e9cules d\u2019Annexine V capables de reconna\u00eetre et de se joindre \u00e0 la phosphatidyls\u00e9rine pr\u00e9sente sur la membrane des spermatozo\u00efdes. La phosphatidyls\u00e9rine est un marqueur pr\u00e9coce de l\u2019apoptose cellulaire. En effet, dans les cellules saines, ce phospholipide se trouve \u00e0 l\u2019int\u00e9rieur de la membrane mais, lors du d\u00e9clenchement de l\u2019apoptose, cette mol\u00e9cule est transf\u00e9r\u00e9e vers l\u2019ext\u00e9rieur de cette membrane. Gr\u00e2ce au MACS, nous sommes ainsi en mesure de d\u00e9tecter ce marqueur sur les spermatozo\u00efdes qui sont pi\u00e9g\u00e9s lorsqu\u2019ils traversent le champ magn\u00e9tique, ce qui nous permet de les s\u00e9parer des spermatozo\u00efdes sains.<\/p>             <\/div>                       <\/div>         <\/div>       <\/div>     <\/div>   <\/div>  <\/section>  <section id=\"dans\" class=\"text-block background-light\">   <div class=\"container\">     <div class=\"row\">       <div class=\"col-12\">         <div class=\"text-block__text-wrapper text-heading-block alignment-left\" data-magic=\"appear-in\">                     <h3 class=\"title-display\">Dans quels cas cette technique est-elle pr\u00e9conis\u00e9e ?<\/h3> <p>Dans quels cas cette technique est-elle pr\u00e9conis\u00e9e ?<\/p> <ul> <li>Les patients qui pr\u00e9sentent un taux anormal de fragmentation de l&rsquo;ADN spermatique.<\/li> <li>Les patientes qui ont d\u00e9j\u00e0 effectu\u00e9 plus de deux cycles de traitement sans obtenir une grossesse.<\/li> <li>Les patientes qui ont fait des fausses-couches \u00e0 r\u00e9p\u00e9tition.<\/li> <\/ul>                   <\/div>       <\/div>     <\/div>   <\/div>  <\/section>   <div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\"> <div class=\"wp-block-column wp-column-is-centred is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:610px\" id=\"votre\"> <h3 class=\"wp-block-heading has-text-align-center\">Votre premi\u00e8re visite<\/h3>    <p class=\"has-text-align-center\">Vous avez la possibilit\u00e9 de r\u00e9aliser votre prem\u00e8re consultation sur place \u00e0 la clinique ou par vid\u00e9oconf\u00e9rence. Choisissez l\u2019option qui vous convient le mieux.<\/p>    <div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-a89b3969 wp-block-buttons-is-layout-flex\"> <div class=\"wp-block-button\"><a class=\"wp-block-button__link has-orange-background-color has-background wp-element-button\" href=\"https:\/\/www.ginefiv.com\/fr\/contact\/\" style=\"border-radius:5px\">Contactez-nous<\/a><\/div> <\/div> <\/div> <\/div>    <section> \t<div class=\"cta-block-container\"> \t\t<div class=\"cta-block-container__title\"> \t\t\t<p><h2>Avez-vous<br \/> des doutes ?<\/h2> <\/p> \t\t<\/div> \t\t<div class=\"cta-block-container__separator d-none d-md-flex\"> \t\t\t<picture> \t\t\t\t<img decoding=\"async\" class=\"separator__img\" src=\"https:\/\/www.ginefiv.com\/wp-content\/themes\/wac-theme\/assets\/images\/icons\/cta-separator.webp\" alt=\"\"> \t\t\t<\/picture> \t\t<\/div> \t\t<div class=\"cta-block-container__icons-row\"> \t\t\t\t\t\t\t<div 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